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Biomedical

Attributable risk from distributed lag models

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Antonio Gasparrini,

Antonio Gasparrini

Michela Leone

Michela Leone

Background

Measures of attributable risk are critical in epidemiology, particularly for planning and evaluating public health interventions. Current definitions, however, often overlook temporal relationships between exposure and risk. This study proposes extended definitions of attributable risk within the framework of distributed l...
Posted 8 months ago

Biomedical

Medical error disclosure: from the therapeutic alliance to risk management: the vision of the new Italian code of medical ethics

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Emanuela Turillazzi,

Emanuela Turillazzi

Margherita Neri

Margherita Neri

Background

The Italian code of medical deontology stipulates that physicians must inform patients of each unwanted event and its causes, identifying, reporting, and evaluating adverse events and errors. This duty extends beyond the doctor-patient relationship and is central to improving professional service quality and clinical risk mana...
Posted 8 months ago

Biomedical

Assessment of reproducibility of cancer survival risk predictions across medical centers

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Hung-Chia Chen,

Hung-Chia Chen

James J Chen

James J Chen

Background

Two key considerations in evaluating survival prediction models are predictability (the ability to accurately predict survival risks) and reproducibility (the ability to generalize predictions across studies or centers). This study explores approaches to assessing the reproducibility of survival risk predictions across medical...
Posted 8 months ago

Biomedical

Loss of international medical experiences: knowledge, attitudes and skills at risk

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Corita R Grudzen,

Corita R Grudzen

Eric Legome

Eric Legome

Key Questions

What are the benefits of international medical experiences?

International medical experiences broaden diagnostic skills, introduce rare clinical entities, improve cultural competence, and increase interest ...
Posted 8 months ago

Biomedical

Coronary age as a risk factor in the modified Framingham risk score

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Enrique F Schisterman,

Enrique F Schisterman

Brian W Whitcomb

Brian W Whitcomb

Summary

The article "Coronary age as a risk factor in the modified Framingham risk score" by Enrique F. Schisterman and Brian W. Whitcomb discusses an improved method for predicting coronary heart disease (CHD) risk by integrating coronary artery calcium (CAC) scores into the traditional Framingham Risk Assessment (FRA). The traditional FR...
Posted 8 months ago

Biomedical

Machine Learning assisted systematic reviewing in orthopaedics

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Bart G. Pijls

Bart G. Pijls

Background

Machine learning assisted systematic reviewing may help to reduce the work burden in systematic reviews. The aim of this study was to determine, through a non-developer, the performance of machine learning assisted systematic reviewing on previously published orthopaedic reviews in retrieving relevant papers.


Posted 8 months ago

Biomedical

Assessing the properties of patient-specific treatment effect estimates from causal forest algorithms under essential heterogeneity

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John M. Brooks,

John M. Brooks

Cole G. Chapman,

Cole G. Chapman

Brian K. Chen,

Brian K. Chen

Sarah B. Floyd,

Sarah B. Floyd

Neset Hikmet

Neset Hikmet

Key Questions

1. What are Causal Forest Algorithms (CFAs)?

CFAs are machine learning methods used to estimate patient-specific treatment effects from observational data, accounting for...
Posted 8 months ago

Biomedical

Use of problem-based learning in orthopaedics education: a systematic review and meta-analysis of randomized controlled trials

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Ting Li,

Ting Li

Ruohong Song,

Ruohong Song

Wenjie Zhong,

Wenjie Zhong

Wenao Liao,

Wenao Liao

Jiang Hu,

Jiang Hu

Xilin Liu,

Xilin Liu

Fei Wang

Fei Wang

Key Questions

1. What are the benefits of Problem-Based Learning (PBL) in orthopaedics education?

PBL significantly improves knowledge scores, procedural skill scores, and clinical ski...
Posted 8 months ago

Biomedical

Selective Schiff Base Formation of Group 9 Organometallic Complexes with Functionalized Spirobifluorene Ligands

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Krystal M. Cid-Seara,

Krystal M. Cid-Seara

Departamento de Química Inorgánica, Universidade de Vigo, Campus Universitario, 36310 Vigo, Spain

Raquel Pereira-Cameselle,

Raquel Pereira-Cameselle

Departamento de Química Orgánica, Universidade de Vigo, Campus Universitario, 36310 Vigo, Spain

Sandra Bolaño,

Sandra Bolaño

Departamento de Química Inorgánica, Universidade de Vigo, Campus Universitario, 36310 Vigo, Spain

Maria Talavera

Maria Talavera

Departamento de Química Inorgánica, Universidade de Vigo, Campus Universitario, 36310 Vigo, Spain

Organic amines are important compounds present in a wide variety of products, which makes the development of new systems for their detection an interesting field of study. New organometallic complexes of group 9 [MCp*X(2′-R-2-py-SBF)] (M = Ir, Rh; R = H, X = Cl (6), R = H, X = OAc (7), R = CHO, X = Cl (8)), and [IrCp*Cl(2′, 7-diCHO-2-py-SBF)] (9) (Cp* pentamethylcyclopentadienyl, SBF =...
Posted 8 months ago

Biomedical

X-Linked Gusher Disease DFNX2 in Children, a Rare Inner Ear Dysplasia with Mixed Hearing and Vestibular Loss

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Soumit Dasgupta,

Soumit Dasgupta

Alder Hey Children’s Hospital NHS Foundation Trust, Eaton Road, Liverpool L14 5AB, UK

James Hong,

James Hong

Faculty of Health and Medical Sciences, University of Liverpool, Liverpool L69 3BX, UK

Rhyanna Morris,

Rhyanna Morris

Faculty of Health and Medical Sciences, University of Liverpool, Liverpool L69 3BX, UK

Javed Iqbal,

Javed Iqbal

East Lancashire Hospitals NHS Trust, Burnley BB10 2PQ, UK

Amy Lennox-Bowley,

Amy Lennox-Bowley

Hypatia Dizziness and Balance Centre, Liverpool L1 9ED, UK

Jeyasakthy Saniasiaya

Jeyasakthy Saniasiaya

Faculty of Medicine, University of Malaya, Kualalampur 50603, Malaysia

Conductive hearing losses are typically present in disorders of the external/middle ear. However, there is a rare group of inner ear conditions called third windows that can also generate a conductive hearing loss. This is due to an abnormal connection between the middle and the inner ear or between the inner ear and the cranial cavity. X-linked gusher disorder is an extremely rare congenital inne...
Posted 8 months ago

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