Research Infinity - All Articles

Physics Maths Engineering

Introducing prediction intervals for sample means

Researchers and practitioners are typically familiar with descriptive statistics and statistical inference. However, outside of regression techniques, little attention may be given to questions around prediction. In the current paper, we introduce prediction intervals using fundamental concepts that are learned in descriptive and inferential statistical training (i.e., sampling error, standard dev...
Posted 8 months ago

Biomedical

Extracellular vesicles and glycans

Highlights • Biological fluids contain nano-sized particles called extracellular vesicles • Extracellular vesicles properties reflect the physiological and pathological state of the parent cells • Extracellular vesicles as analytes are suitable for use in liquid biopsy-based real-time diagnostics • Glycans, complex oligosaccharides, are distinct components of extracellular vesicles mem...
Posted 8 months ago

Biomedical

Glucose inhibitor tubes in Croatian laboratories: are we doing well?

Introduction Reliable and accurate measurement of blood glucose concentration is of crucial importance for making clinical decisions in diagnosis diabetes, gestational diabetes and impaired fasting glucose tolerance. Materials and methods Survey was performed in form of questionnaire. Questionnaire was sent to all Croatian laboratories (N = 204) in electronic form using SurveyMonkey cloud-bas...
Posted 8 months ago

Biomedical

What did CRISPR-Cas9 accomplish in its first 10 years?

It’s been 10 years now from the debut of clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) era in which gene engineering has never been so accessible, precise and efficient. This technology, like a refined surgical procedure, has offered the ability of removing different types of disease causing mutations and restoring key proteins activity with ease of...
Posted 8 months ago

Biomedical

Preanalytical, analytical and postanalytical considerations in circulating microRNAs measurement

Highlights • Methods used for miRNAs expression profiling are quantitative reverse transcription polymerase chain reaction, microarrays, next generation sequencing and droplet digital PCR • To obtain reproducible and accurate miRNAs expression profiling detection, it is crucial to strictly standardize the entire process, starting from choosing the specimen type until the normalization strate...
Posted 8 months ago

Biomedical

Antiphospholipid antibodies in patients with antiphospholipid syndrome

Highlights • Antiphospholipid syndrome is a rare systemic autoimmune disease characterized by recurrent pregnancy morbidity or thrombosis in combination with the persistent presence of antiphospholipid antibodies in plasma/serum • Specialists in laboratory medicine should take responsibility for the entire analytical process, so that possible interferences are minimized, and physicians obtai...
Posted 8 months ago

Physics Maths Engineering

Climate Change and Livestock Production in Nigeria: Issues and Concerns

Nwosu and Ogbu (2011) provide a comprehensive overview of the challenges posed by climate change to livestock production in Nigeria. They emphasize the need for adaptive measures to address the adverse effects of climate variability on livestock health and productivity. The review underscores the importance of integrating environmental modifications, selective breeding, and nutritional adjustme...
Posted 8 months ago

Biomedical

Growth and Progression of TRAMP Prostate Tumors in Relationship to Diet and Obesity

To clarify effects of diet and body weight on prostate cancer development, three studies were undertaken using the TRAMP mouse model of this disease. In the first experiment, obesity was induced by injection of gold thioglucose (GTG). Age of prostate tumor detection (~33 wk) and death (~43 wk) was not significantly different among the groups. In the second study, TRAMP-C2 cells were injected i...
Posted 8 months ago

Biomedical

Relationship among muscle strength, muscle endurance, and skeletal muscle oxygenation dynamics during ramp incremental cycle exercise

Peak oxygen uptake (VO2), evaluated as exercise tolerance, is a strong predictor of life prognosis regardless of health condition. Several previous studies have reported that peak VO2 is higher in those with a greater decrease in muscle oxygen saturation (SmO2) in the active muscles during incremental exercise. However, the skeletal muscle characteristics of individuals exhibiting a greater decrea...
Posted 8 months ago

Biomedical

Influence of an Inspiratory Muscle Fatigue Protocol on Older Adults on Respiratory Muscle Strength, Muscle Oxygen Saturation, and Functional Capacity. A randomized controlled trial

Background The fatigue of the inspiratory musculature, particularly the diaphragm, has been demonstrated to exert systemic effects on the body, impacting cardiovascular and performance outcomes. This study aimed to evaluate the influence of an inspiratory muscle fatigue protocol on respiratory muscle strength, functionality, and muscle oxygen saturation in older adults. Methods A double-blinded...
Posted 8 months ago