Research Infinity - All Articles

Biomedical

Fabrication and Testing of a PET insert for Simultaneous PET/FUS/MRI

Glioblastoma (GB) is the most common brain cancer and has limited survivability with a mean survival time of 15 months and an overall survival of less than 7 % after 5 years. Impediments to delivery of large molecule (e.g. antibodies) and cell therapeutics to a tumor include the blood–brain barrier (BBB) and the blood‐tumor barrier (BTB) which prevent large solutes from crossing from circulati...
Posted 8 months ago

Biomedical

Effects of PET image reconstruction parameters and tumor-to-background uptake ratio on quantification of PET images from PET/MRI and PET/CT systems

PET/CT and PET/MRI are valuable multimodality imaging techniques for visualizing both functional and anatomical information. The most used PET reconstruction algorithm is Ordered Subset Expectation Maximization (OSEM). In OSEM, the image noise increases with increased number of iterations, and the reconstruction needs to be stopped before complete convergence. The Bayesian penalized likelihood (BP...
Posted 8 months ago

Biomedical

18F-FDG PET-CT Scans in Oncology Patients Treated with Hyaluronic Acid Filler: Not Always a Pitfall

The use of hyaluronic acid (HA) fillers in oncology patients undergoing PET-CT scans is a topic of debate due to potential interference with imaging accuracy. A 54-year-old female, postmelanoma metastasectomy in the parotid region with subsequent facial nerve palsy (FNP), received HA filler injections for facial symmetry and functional restoration. Follow-up PET-CT scans showed no interference or ...
Posted 8 months ago

Biomedical

A Systematic Review on Artificial Intelligence Evaluating Metastatic Prostatic Cancer and Lymph Nodes on PSMA PET Scans

Early detection of metastatic prostate cancer (mPCa) is crucial. Whilst the prostate-specific membrane antigen (PSMA) PET scan has high diagnostic accuracy, it suffers from inter-reader variability, and the time-consuming reporting process. This systematic review was registered on PROSPERO (ID CRD42023456044) and aims to evaluate AI’s ability to enhance reporting, diagnostics, and predic...
Posted 8 months ago

Physics Maths Engineering

Adapting power calculations to include a superiority margin: what are the implications?

This paper examines the application of super-superiority margins in study power calculations. Unlike traditional power calculations, which primarily aim to reject the null hypothesis by any margin, a super-superiority margin establishes a clinically significant threshold. Despite potential benefits, this approach, akin to a non-inferiority calculation but in an opposing direction, is rarely use...
Posted 9 months ago

No Category

A Comparative Analysis of COVID-19 Response Measures and Their Impact on Mortality Rate

(1) Background: The coronavirus disease 2019 (COVID-19) pandemic significantly affected the population worldwide, with varying responses implemented to control its spread. This study aimed to compare the epidemic data compiled by the World Health Organization (WHO) to understand the impact of the measures adopted by each country on the mortality rate. (2) Methods: The increase or decrease ...
Posted 9 months ago

No Category

Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy

AbstractBiallelic (autosomal recessive) pathogenic variants in ATP13A2 cause a form of juvenile-onset parkinsonism, termed Kufor-Rakeb syndrome. In addition to motor symptoms, a variety of other neurological and psychiatric symptoms may occur in affected individuals, including supranuclear gaze palsy and cognitive decline. Although psycho...
Posted 9 months ago

Biomedical

Development and implementation of a simple and rapid extraction-free saliva SARS-CoV-2 RT-LAMP workflow for workplace surveillance

Effective management of the COVID-19 pandemic requires widespread and frequent testing of the population for SARS-CoV-2 infection. Saliva has emerged as an attractive alternative to nasopharyngeal samples for surveillance testing as it does not require specialized personnel or materials for its collection and can be easily provided by the patient. We have developed a simple, fast, and sens...
Posted 10 months ago

Physics Maths Engineering

Investigation on the Excitation Function of Alpha Induced Reaction on 116-Cd in the Energy Range between 15 and 40 Mev

In this work, the alpha particle-induced reaction on Cadmium-116 in the energy range 20-40 MeV has been studied. The excitation function for the following reaction channels of this type have been studied in the energy range of 15 MeV-40 MeV are; 48-Cd-116(α, n) 50-Sn-119. This reaction has a total number of exciton six, number of neutron one and number of holes also one. 48-Cd-116(α, 2n + p) 49-...
Posted 1 year ago

Physics Maths Engineering

HYBRID SCHEMES BASED ON WAVELET TRANSFORM AND CONVOLUTIONAL AUTO-ENCODER FOR IMAGE COMPRESSION

In recent years, image compression techniques have received a lot of attention from researchers as the number of images at hand keep growing. Digital Wavelet Transform is one of them that has been utilized in a wide range of applications and has shown its efficiency in image compression field. Moreover, used with other various approaches, this compression technique has proven its ability to compre...
Posted 2 years ago