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Biomedical

Pregnancy and Risk of Intracerebral Hemorrhage

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Institution: rnfinity

Email: info@rnfinity.com

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Kazuyoshi Aoyama,

Kazuyoshi Aoyama

Institution: Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada

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Joel G. Ray

Joel G. Ray

Institution: Department of Medicine, University of Toronto, Ontario, Canada

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The study highlights pregnancy's role in increasing the risk of intracerebral hemorrhage (ICH), especially within the first 12 weeks postpartum. Key risk factors include chronic hypertension, gestational hypertension, and preeclampsia. Treatment strategies focus on blood pressure control, the use of low-dose aspirin for high-risk women, and managing coagulation issues. Timely diagnosis and neuroim...
Posted 6 months ago

Biomedical

Electronic Fetal Monitoring—Imperfect but Opportunities for Improvement

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Institution: rnfinity

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Aaron B. Caughey

Aaron B. Caughey

Institution: Department of Obstetrics and Gynecology, Oregon Health & Science University, Portland

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Electronic fetal monitoring (EFM) has limitations in detecting fetal hypoxia and acidemia, and clinicians often do not act on abnormal readings. Recent studies suggest that improving clinician training, refining monitoring algorithms, and establishing standardized protocols can help prevent neonatal encephalopathy. Despite its flaws, EFM presents opportunities to enhance neonatal outcomes through ...
Posted 6 months ago

Biomedical

Do Patients Care What Their X-rays Look Like?

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Institution: rnfinity

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Matthew Costa

Matthew Costa

Institution: Oxford Trauma, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences, Medical Sciences Division, University of Oxford, Oxford, United Kingdom

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The study by Chung et al. shows that radiographic parameters of distal radius fractures have little association with patient-reported and objective functional outcomes. This suggests that surgeons should focus more on low-risk, effective interventions for returning patients to function rather than stressing precise anatomical restoration. Surgical procedures may still be necessary for severely dis...
Posted 6 months ago

Biomedical

Tobacco Use in High-Risk Populations

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Institution: rnfinity

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Wilson M. Compton,

Wilson M. Compton

Institution: National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland

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Emily B. Einstein

Emily B. Einstein

Institution: National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland

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The study by Akhtar and colleagues highlights the high rate of tobacco use (over 90%) among rural individuals who inject drugs, revealing the ongoing smoking epidemic in high-risk populations. Tobacco use is linked to social stressors like Medicaid insurance and homelessness. The study suggests that smoking cessation interventions have not effectively reached this group, and advocates for integrat...
Posted 6 months ago

Biomedical

The Uncertain Science of Predicting Death

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Institution: rnfinity

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Laura Van Metre Baum,

Laura Van Metre Baum

Institution: Division of Hematology and Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee

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Debra Friedman

Debra Friedman

Institution: Division of Pediatric Hematology/Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee

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The study by Seow et al. explores the development of a patient-oriented prognostic tool to help patients with cancer understand their mortality and disease trajectory. It aims to improve end-of-life (EOL) care by empowering patients to make informed decisions aligned with their goals. The study highlights the importance of prognosis awareness, functional decline, and symptom monitoring in improvin...
Posted 6 months ago

Biomedical

Managing Uncertainty in Prenatal Diagnosis of Congenital Heart Disease

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Institution: rnfinity

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Alun C. Jackson

Alun C. Jackson

Institution: Australian Centre for Heart Health, Melbourne, Victoria, Australia

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The study focuses on the emotional challenges faced by parents dealing with a prenatal congenital heart disease (CHD) diagnosis, particularly the uncertainty surrounding the condition’s severity and long-term impacts. It suggests integrating palliative care techniques to help pediatric cardiologists support families better. Key recommendations include using more positive terminology like “hear...
Posted 6 months ago

Physics Maths Engineering

Limitations of Meta-analyses of Studies With High Heterogeneity

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Institution: rnfinity

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Peter B. Imrey

Peter B. Imrey

Institution: Department of Quantitative Health Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio

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Sabitova et al have performed an important service in compiling and summarizing 2 decades of studies on job burnout and satisfaction among physicians and dentists in middle-income countries and a few low-income countries. The authors followed a standard approach to performing a systematic review and meta-analysis to analyze studies that assessed job-related morale among physicians and dentists wor...
Posted 6 months ago

Biomedical

Challenges in Predicting Lyme Disease Risk

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Institution: rnfinity

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Kiersten J. Kugeler,

Kiersten J. Kugeler

Institution: Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado

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Rebecca J. Eisen

Rebecca J. Eisen

Institution: Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado

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The article discusses the challenges in predicting Lyme disease risk due to incomplete and inconsistent data. Although Lyme disease incidence is increasing, accurate prediction models are hindered by gaps in tick distribution, infection prevalence, and human disease surveillance. The authors emphasize the need for more accurate and standardized data, particularly regarding the presence of infected...
Posted 6 months ago

Biomedical

How Should Surveillance Systems Account for Concurrent Intravascular Catheters?

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Institution: rnfinity

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Leonard A. Mermel

Leonard A. Mermel

Institution: Department of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island

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The risk of central venous catheter (CVC)-associated bloodstream infections has decreased dramatically.1 The same may not be true for infections associated with short-term peripheral venous catheters.2 The effects of future preventive efforts should be measured using data derived from evidence-based surveillance programs. Dube et al3 describe a multicenter, retrospective cohort study that assessed...
Posted 6 months ago

Biomedical

Unexpected abnormal coagulation test results in a 2-year-old child

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Institution: rnfinity

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Patricija Banković Radovanović,

Patricija Banković Radovanović

Institution: Department of transfusion medicine, General Hospital Pula, Pula, Croatia

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Tanja Živković Mikulčić,

Tanja Živković Mikulčić

Institution: Department of transfusion medicine, General Hospital Pula, Pula, Croatia

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Jasmina Simović Medica

Jasmina Simović Medica

Institution: Department of transfusion medicine, General Hospital Pula, Pula, Croatia

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Rejection of the sample with repeated blood withdrawal is always an unwanted consequence of sample nonconformity and preanalytical errors, especially in the most vulnerable population – children. Here is presented a case with unexpected abnormal coagulation test results in a 2-yearold child with no previously documented coagulation disorder. Child is planned for tympanostomy tubes removal unde...
Posted 6 months ago

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