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Biochemistry

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If you’re engaged in cutting-edge biochemistry research and want your ideas to reach the global academic community — without the wait and restrictions of peer reviewed articles — we invite you to submit to our platform's Biochemistry section. Here, we believe in giving authors visibility and offering them the rare opportunity to monetize their work.

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From molecular interactions to enzyme functions and protein structure, biochemistry is a cornerstone of modern science. Whether you're a seasoned academic or an early-career researcher, your contributions in the form of scientific articles and biochemical research can help shape new discoveries. Unlike traditional peer reviewed journal articles, our system allows you to publish without long delays while earning from your work.

From Academia to Application

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For Students, Educators, and Independent Researchers

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A Fair Model: Publish and Earn

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Join our growing community of scientists, scholars, and independent thinkers. Submit your biochemistry article today and let your research inspire and educate others — while you earn for the work you’ve already invested in.

Biomedical

Epidermal Differentiation Genes of the Common Wall Lizard Encode Proteins with Extremely Biased Amino Acid Contents

Karin Brigit Holthaus,

Karin Brigit Holthaus

Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria

Attila Placido Sachslehner,

Attila Placido Sachslehner

Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria

Julia Steinbinder,

Julia Steinbinder

Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria

Leopold Eckhart

Leopold Eckhart

Department of Dermatology, Medical University of Vienna, 1090 Vienna, Austria


The epidermal differentiation complex (EDC) is a cluster of genes that code for protein components of cornified cells on the skin surface of amniotes. Squamates are the most species-rich clade of reptiles with skin adaptations to many different environments. As the genetic regulation of the skin epidermis and its evolution has been characterized for only a few species so far, we aimed to determine...
7 months ago

Biomedical

Unexpected abnormal coagulation test results in a 2-year-old child

Patricija Banković Radovanović,

Patricija Banković Radovanović

Department of transfusion medicine, General Hospital Pula, Pula, Croatia

Tanja Živković Mikulčić,

Tanja Živković Mikulčić

Department of transfusion medicine, General Hospital Pula, Pula, Croatia

Jasmina Simović Medica

Jasmina Simović Medica

Department of transfusion medicine, General Hospital Pula, Pula, Croatia


Rejection of the sample with repeated blood withdrawal is always an unwanted consequence of sample nonconformity and preanalytical errors, especially in the most vulnerable population – children. Here is presented a case with unexpected abnormal coagulation test results in a 2-yearold child with no previously documented coagulation disorder. Child is planned for tympanostomy tubes removal unde...
7 months ago

Biomedical

Affordable Biologics for All

Joel Lexchin

Joel Lexchin

School of Health Policy and Management, Faculty of Health, York University, Toronto, Ontario, Canada


To paraphrase something that Mark Twain is alleged to have said, “Everybody talks about drug prices, but nobody does anything about them.” The last part of the paraphrase is not quite accurate, but to date, none of the major federal proposals to lower drug prices have been enacted, and state legislation, such as the California Preserving Access to Affordable Drugs Act, is under legal challenge...
7 months ago

Biomedical

Diagnostic role of urine human epididymis protein 4 in ovarian cancer

Antonija Hanžek,

Antonija Hanžek

Christian Siatka,

Christian Siatka

Anne-Cécile E. Duc

Anne-Cécile E. Duc


Urine human epididymis protein 4 (HE4) is a promising, non-invasive tumor marker for ovarian cancer (OC), offering advantages in early detection and monitoring. Studies show urine HE4 concentrations are higher than serum levels, with comparable sensitivity and specificity for detecting OC. It can aid in the differential diagnosis, monitor chemotherapy response, and track disease recurrence. Howeve...
7 months ago

Biomedical

Clinical importance of laboratory biomarkers in liver fibrosis

Valdas Banys,

Valdas Banys

Department of Physiology, Biochemistry, Microbiology and Laboratory Medicine, Faculty of Medicine, Vilnius University, Vilnius, Lithuania

Goda Aleknavičiūtė-Valienė

Goda Aleknavičiūtė-Valienė

Center of Laboratory Medicine,Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania


Hepatic cirrhosis is a major health problem across the world, causing high morbidity and mortality. This disease has many etiologies, yet the result of chronic hepatic injury is hepatic fibrosis causing cirrhosis and hepatocellular carcinoma, as the liver’s architecture is progressively destroyed. While liver biopsy is currently the gold standard for fibrosis staging, it has significant disadvan...
7 months ago

Biomedical

A sudden creatinine increase: A case report

Bernhard Strasser,

Bernhard Strasser

Kepler University Hospital Linz, Institute of Laboratory Medicine, Linz, Austria

Sebastian Strasser,

Sebastian Strasser

Medical University of Vienna, Vienna, Austria

Josef Tomasits

Josef Tomasits

Kepler University Hospital Linz, Institute of Laboratory Medicine, Linz, Austria


Creatinine and estimated glomerular filtration rate (eGFR) are first-line laboratory parameters in the diagnosis of various renal diseases. In recent decades, cystatin C (cysC) has furthered the laboratory repertoire regarding renal status assessment and has been implemented in many clinical guidelines. Accordingly, with the establishment of cysC as a renal routine biomarker, further opportunities...
7 months ago

Biomedical

Underfilled blood tube containing EDTA

Murat Can,

Murat Can

Berrak Guven,

Berrak Guven

Ismail Benice

Ismail Benice


Introduction Blood samples having inappropriate volume are a substantial part of preanalytical errors. Inadequate sample volume for glycated haemoglobin (HbA1c) test may be a common problem of patients with diabetes mellitus having vascular changes. In this study, we compared HbA1c concentrations of underfilled and appropriately filled blood collection tubes. Materials and methods To compare Hb...
7 months ago

Biomedical

Defining laboratory medicine, or squaring the circle?

Joseph Watine

Joseph Watine

Laboratoire de biologie polyvalente, Hôpital général, Villefranche-de-Rouergue, France


In the August 2020 issue of Clinical Chemistry and Laboratory Medicine, Giuseppe Lippi and Mario Plebani proposed a definition of laboratory medicine, which ends with this sentence: “The results of these measurements are translated into actionable information for improving the care and/or maintaining the wellness of both a single individual and an entire population”. Nevertheless, the selfishn...
7 months ago

Biomedical

Complete blood count alterations in COVID-19 patients

Mariangela Palladino

Mariangela Palladino

Emergency Department, Umberto I University Hospital, Rome, Italy


Coronavirus disease 2019 (COVID-19) pandemic represents a scientific and social crisis. One of the main unmet needs for coronavirus disease 2019 is its unpredictable clinical course, which can rapidly change in an irreversible outcome. COVID-19 patients can be classified into mild, moderate, and severe. Several haematological parameters, such as platelets, white blood cell total count, lymphocytes...
7 months ago

Biomedical

Extracellular vesicles and glycans

Tamara Janković,

Tamara Janković

Miroslava Janković

Miroslava Janković


Highlights • Biological fluids contain nano-sized particles called extracellular vesicles • Extracellular vesicles properties reflect the physiological and pathological state of the parent cells • Extracellular vesicles as analytes are suitable for use in liquid biopsy-based real-time diagnostics • Glycans, complex oligosaccharides, are distinct components of extracellular vesicles mem...
7 months ago

Related Subjects

Anatomy Epidemiology Genetics Neuroscience Psychology Oncology Medicine Musculoskeletal science Pediatrics Pathology Pharmacology Physiology Psychiatry Primary care Women and reproductive health

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