Matthias Wjst
Matthias Wjst
Institution:
Email:
The article "Caught you: threats to confidentiality due to the public release of large-scale genetic data sets" by Matthias Wjst examines the ethical implications of sharing large-scale genetic data for research purposes. It highlights the risks associated with the assumption that anonymizing genetic data fully protects individual privacy. The study identifies two primary re-identification meth...
Posted 6 months ago
Faten Mane Aldhafeeri
Faten Mane Aldhafeeri
Institution:
Email:
Background
The integration of artificial intelligence (AI) in radiography presents transformative opportunities for diagnostic imaging and introduces complex ethical considerations. The aim of this cross-sectional study was to explore radiographers’ perspectives on the ethical implications of AI in their field and identify key...
Posted 6 months ago
Julie Allard,
Julie Allard
Institution:
Email:
Fabian Ballesteros,
Fabian Ballesteros
Institution:
Email:
Marie-Chantal Fortin
Marie-Chantal Fortin
Institution:
Email:
Background
Medical assistance in dying (MAID) has been legal in Québec since December 2015 and in the rest of Canada since July 2016. Since then, more than 60 people have donated their organs after MAID. Such donations raise ethical issues about respect of patients’ autonomy, potential pressure to choose MAID, the informat...
Posted 6 months ago
Sylvia Martin,
Sylvia Martin
Institution:
Email:
Mirko Ancillotti,
Mirko Ancillotti
Institution:
Email:
Santa Slokenberga,
Santa Slokenberga
Institution:
Email:
Amal Matar
Amal Matar
Institution:
Email:
Background
In this study, we examined the ethical implications of Egypt’s new clinical trial law, employing the ethical framework proposed by Emanuel et al. and comparing it to various national and supranational laws. This analysis is crucial as Egypt, considered a high-growth pharmaceutical market, has become an attractive lo...
Posted 6 months ago
Silviya Aleksandrova-Yankulovska,
Silviya Aleksandrova-Yankulovska
Institution:
Email:
Florian Steger
Florian Steger
Institution:
Email:
Abstract
Background
In the last decades all health systems have experienced a lack of resources. Against this background, the idea of applying personal responsibility of the patient as a criterion for allocation of resources (PRCAR) is gaining increasing attention. Bu...
Posted 6 months ago
Physics Maths Engineering
Walerian Arabczyk,
Walerian Arabczyk
Institution: Department of Inorganic Chemical Technology and Environment Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Ave. 42, 71-065 Szczecin, Poland
Email:
Rafał Pelka,
Rafał Pelka
Institution: Department of Inorganic Chemical Technology and Environment Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Ave. 42, 71-065 Szczecin, Poland
Email:
Izabella Jasińska,
Izabella Jasińska
Institution: Grupa Azoty Zakłady Chemiczne “Police” S.A., 1 Kuźnicka Str., 72-010 Police, Poland
Email:
Zofia Lendzion-Bieluń
Zofia Lendzion-Bieluń
Institution: Department of Inorganic Chemical Technology and Environment Engineering, Faculty of Chemical Technology and Engineering, West Pomeranian University of Technology in Szczecin, Piastów Ave. 42, 71-065 Szczecin, Poland
Email:
Key Takeaways
Thermodynamic Stability
- The study presents a model demonstrating the thermodynamic parameters that govern the iron catalyst sintering process, focusing on stability aspects of nanocrystalline structures.
Catalyst Activation Mechanisms
...
Posted 6 months ago
Physics Maths Engineering
José Jiménez,
José Jiménez
Institution: Department of Electronics, University of Alcalá, Alcalá de Henares, Madrid 28805, Spain
Email:
Francisco Meca,
Francisco Meca
Institution: Department of Electronics, University of Alcalá, Alcalá de Henares, Madrid 28805, Spain
Email:
Enrique Santiso,
Enrique Santiso
Institution: Department of Electronics, University of Alcalá, Alcalá de Henares, Madrid 28805, Spain
Email:
Pedro Martín
Pedro Martín
Institution: Department of Electronics, University of Alcalá, Alcalá de Henares, Madrid 28805, Spain
Email:
Key Questions
What is a chalcographic printer?
A chalcographic printer is a type of press used to transfer ink from an engraved metal plate onto paper, essential in printing processes requiring high precision, like currency production. This system relies ...
Posted 6 months ago
Physics Maths Engineering
Kwabena Boakye,
Kwabena Boakye
Institution: Research Institute for Clean Growth and Future Mobility, Coventry University, Coventry CV1 5FB, UK
Email:
Morteza Khorami
Morteza Khorami
Institution: School of Energy, Construction & Environment, College of Engineering, Environment and Science, Coventry University, Coventry CV1 5FB, UK
Email:
Key Answers
What materials can be used to create sustainable self-compacting concrete?
This study found that self-compacting concrete (SCC) can effectively incorporate steel slag and calcined clay as partial replacements for traditional Portland cement. These materials improve sustainability by reducing reliance on c...
Posted 6 months ago
Physics Maths Engineering
Roderick J. Lawrence
Roderick J. Lawrence
Institution: Geneva School of Social Sciences (G3S), Institute for Environmental Sciences (ISE), University of Geneva, 1211 Geneva, Switzerland
Email:
The article "Promoting and Sustaining Urban Health: Challenges and Responses" by Roderick J. Lawrence examines the complex interplay between urbanization and health, emphasizing the need for integrated approaches to address health challenges in rapidly urbanizing environments. The study underscores the importance of understanding the multifaceted relationships between urban and planetary health...
Posted 6 months ago
Physics Maths Engineering
Uwe Waller
Uwe Waller
Institution: School of Engineering, Saarland University of Applied Sciences (HTW Saar), Goebenstraße 40, 66117 Saarbrücken, Germany
Email:
A recirculating aquaculture system (RAS) represents a forward-looking form of aquaculture. A RAS consists of fish tanks and water treatment processes in a closed loop to sustain the environmental conditions for fish production. However, the rapid industrialization of the technology is fraught with transfer problems. This review justifies a RAS process chain based on fish biology. The under...
Posted 6 months ago
Velin Kralev,
Velin Kralev
Institution: Department of Informatics, Faculty of Mathematics and Natural Sciences, South-West University, 2700 Blagoevgrad, Bulgaria
Email:
Radoslava Kraleva
Radoslava Kraleva
Institution: Department of Informatics, Faculty of Mathematics and Natural Sciences, South-West University, 2700 Blagoevgrad, Bulgaria
Email:
This research is focused on evolutionary algorithms, with genetic and memetic algorithms discussed in more detail. A graph theory problem related to finding a minimal Hamiltonian cycle in a complete undirected graph (Travelling Salesman Problem—TSP) is considered. The implementations of two approximate algorithms for solving this problem, genetic and memetic, are presented. The main obje...
Posted 6 months ago
Physics Maths Engineering
Pratik Thantharate,
Pratik Thantharate
Institution: SUNY Binghamton, Jersey City, NJ 07304, USA
Email:
Shyam Bhojwani,
Shyam Bhojwani
Institution: SUNY Binghamton, Jersey City, NJ 07304, USA
Email:
Anurag Thantharate
Anurag Thantharate
Institution: School of Computing and Engineering, University of Missouri, Kansas City, MO 64112, USA
Email:
The proliferation of cloud computing has amplified the need for robust privacy-preserving technologies, particularly when dealing with sensitive financial and human resources (HR) data. However, traditional differential privacy methods often struggle to balance rigorous privacy protections with maintaining data utility. This study introduces DPShield, an optimized adaptive framework that e...
Posted 6 months ago
Physics Maths Engineering
Rakhee Ramachandran,
Rakhee Ramachandran
Institution: School of Water, Energy and Environment, Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, UK
Email:
Yadira Bajón Fernández,
Yadira Bajón Fernández
Institution: School of Water, Energy and Environment, Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, UK
Email:
Ian Truckell,
Ian Truckell
Institution: School of Water, Energy and Environment, Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, UK
Email:
Carlos Constantino,
Carlos Constantino
Institution: Atkins Limited, One St Aldates, St Aldate’s, Oxford OX1 1DE, UK
Email:
Richard Casselden,
Richard Casselden
Institution: Atkins Limited, The Hub, 500 Park Avenue, Aztec West, Almondsbury, Bristol BS32 4RZ, UK
Email:
Paul Leinster,
Paul Leinster
Institution: School of Water, Energy and Environment, Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, UK
Email:
Mónica Rivas Casado
Mónica Rivas Casado
Institution: School of Water, Energy and Environment, Cranfield University, College Road, Cranfield, Bedfordshire MK43 0AL, UK
Email:
With the increase in rainfall intensity, population, and urbanised areas, surface water flooding (SWF) is an increasing concern impacting properties, businesses, and human lives. Previous studies have shown that microtopography significantly influences flow paths, flow direction, and velocity, impacting flood extent and depth, particularly for the shallow flow associated with urban SWF. Th...
Posted 6 months ago
Zhongbo Liu,
Zhongbo Liu
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
Liankun Song,
Liankun Song
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
Jun Xie,
Jun Xie
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
Xue-Ru Wu,
Xue-Ru Wu
Institution: Department of Urology, NYU School of Medicine, New York, NY 10016, USA
Email:
Greg E. Gin,
Greg E. Gin
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
Beverly Wang,
Beverly Wang
Institution: Department of Pathology and Laboratory Medicine, University of California, Irvine, Orange, CA 92868, USA
Email:
Edward Uchio,
Edward Uchio
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
Xiaolin Zi
Xiaolin Zi
Institution: Department of Urology, University of California Irvine, Orange, CA 92868, USA
Email:
UPII-mutant Ha-ras transgenic mice develop urothelial hyperplasia and low-grade papillary carcinoma, which mimics human non-muscle invasive bladder cancer (NMIBC). We investigated the effects and mechanisms of kawain, a main kavalactone in the kava plant, on oncogenic Ha-ras-driven urothelial carcinoma in these mice. The mice were fed at six weeks of age with vehicle control or kawain (6 g...
Posted 6 months ago
James P. C. Coverdale,
James P. C. Coverdale
Institution: School of Pharmacy, Institute of Clinical Sciences, University of Birmingham, Edgbaston B15 2TT, UK
Email:
Sirilata Polepalli,
Sirilata Polepalli
Institution: Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK
Email:
Marco A. Z. Arruda,
Marco A. Z. Arruda
Institution: Institute of Chemistry, Department of Analytical Chemistry, Universidade Estadual de Campinas, Campinas 13083-970, Brazil
Email:
Ana B. Santos da Silva,
Ana B. Santos da Silva
Institution: Institute of Chemistry, Department of Analytical Chemistry, Universidade Estadual de Campinas, Campinas 13083-970, Brazil
Email:
Alan J. Stewart,
Alan J. Stewart
Institution: School of Medicine, University of St. Andrews, St Andrews KY16 9TF, UK
Email:
Claudia A. Blindauer
Claudia A. Blindauer
Institution: Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK
Email:
Interactions between proteins and metal ions and their complexes are important in many areas of the life sciences, including physiology, medicine, and toxicology. Despite the involvement of essential elements in all major processes necessary for sustaining life, metalloproteomes remain ill-defined. This is not only owing to the complexity of metalloproteomes, but also to the non-covalent c...
Posted 6 months ago
Rumit Patel,
Rumit Patel
Institution: Department of Agricultural Biotechnology, Anand Agricultural University, Anand 388110, India
Email:
Juned Memon,
Juned Memon
Institution: Department of Genetics and Plant Breeding, B. A. College of Agriculture, Anand Agricultural University, Anand 388110, India
Email:
Sushil Kumar,
Sushil Kumar
Institution: Department of Agricultural Biotechnology, Anand Agricultural University, Anand 388110, India
Email:
Dipak A. Patel,
Dipak A. Patel
Institution: Department of Agricultural Biotechnology, Anand Agricultural University, Anand 388110, India
Email:
Amar A. Sakure,
Amar A. Sakure
Institution: Department of Agricultural Biotechnology, Anand Agricultural University, Anand 388110, India
Email:
Manish B. Patel,
Manish B. Patel
Institution: Main Maize Research Station, Anand Agricultural University, Godhra 389001, India
Email:
Arna Das,
Arna Das
Institution: Department of Genetics and Plant Breeding, B. A. College of Agriculture, Anand Agricultural University, Anand 388110, India
Email:
Chikkappa G. Karjagi,
Chikkappa G. Karjagi
Institution: ICAR—Indian Institute of Maize Research, PAU Campus, Ludhiana 141004, India
Email:
Swati Patel,
Swati Patel
Institution: Department of Agricultural Biotechnology, Anand Agricultural University, Anand 388110, India
Email:
Ujjaval Patel,
Ujjaval Patel
Institution: Department of Genetics and Plant Breeding, N. M. College of Agriculture, Navsari Agricultural University, Navsari 396450, India
Email:
Rajib Roychowdhury
Rajib Roychowdhury
Institution: Department of Plant Pathology and Weed Research, Institute of Plant Protection, Agricultural Research Organization (ARO)—Volcani Center, Rishon Lezion 7505101, Israel
Email:
Maize (Zea mays L.) is an important cereal and is affected by climate change. Therefore, the production of climate-smart maize is urgently needed by preserving diverse genetic backgrounds through the exploration of their genetic diversity. To achieve this, 96 maize inbred lines were used to screen for phenotypic yield-associated traits and grain quality parameters. These traits were studie...
Posted 6 months ago
Physics Maths Engineering
Norman Pelak,
Norman Pelak
Institution: Hydrologic Research Center, San Diego, CA 92127, USA
Email:
Eylon Shamir,
Eylon Shamir
Institution: Hydrologic Research Center, San Diego, CA 92127, USA
Email:
Theresa Modrick Hansen,
Theresa Modrick Hansen
Institution: Hydrologic Research Center, San Diego, CA 92127, USA
Email:
Zhengyang Cheng
Zhengyang Cheng
Institution: Hydrologic Research Center, San Diego, CA 92127, USA
Email:
Operational forecasters desire information about how their reservoir and riverine systems will evolve over monthly to seasonal timescales. Seasonal traces of hydrometeorological variables at a daily or sub-daily resolution are needed to drive hydrological models at this timescale. Operationally available models such as the Climate Forecast System (CFS) provide seasonal precipitation foreca...
Posted 6 months ago
Mònica Campàs,
Mònica Campàs
Institution: IRTA, Marine and Continental Waters (AMiC) Programme, Ctra. Poble Nou del Delta, km. 5.5, 43540 La Ràpita, Spain
Email:
Jaume Reverté,
Jaume Reverté
Institution: IRTA, Marine and Continental Waters (AMiC) Programme, Ctra. Poble Nou del Delta, km. 5.5, 43540 La Ràpita, Spain
Email:
Àngels Tudó,
Àngels Tudó
Institution: Department of Basic Medical Sciences, Universitat Rovira i Virgili, C/Sant Llorenç 21, 43201 Reus, Spain
Email:
Mounira Alkassar,
Mounira Alkassar
Institution: IRTA, Marine and Continental Waters (AMiC) Programme, Ctra. Poble Nou del Delta, km. 5.5, 43540 La Ràpita, Spain
Email:
Jorge Diogène,
Jorge Diogène
Institution: IRTA, Marine and Continental Waters (AMiC) Programme, Ctra. Poble Nou del Delta, km. 5.5, 43540 La Ràpita, Spain
Email:
Francesc X. Sureda
Francesc X. Sureda
Institution: Department of Basic Medical Sciences, Universitat Rovira i Virgili, C/Sant Llorenç 21, 43201 Reus, Spain
Email:
Tetrodotoxin (TTX) is a marine toxin responsible for many intoxications around the world. Its presence in some pufferfish species and, as recently reported, in shellfish, poses a serious health concern. Although TTX is not routinely monitored, there is a need for fast, sensitive, reliable, and simple methods for its detection and quantification. In this work, we describe the use of an auto...
Posted 6 months ago
Physics Maths Engineering
Dennis A. Mwalongo,
Dennis A. Mwalongo
Institution: Tanzania Atomic Energy Commission, Directorate of Nuclear Technology and Technical Services, Arusha P.O. Box 743, Tanzania
Email:
Nils H. Haneklaus,
Nils H. Haneklaus
Institution: Nelson Mandela African Institution of Science and Technology (NM-AIST), School for Materials, Energy, Water, Environmental Science and Engineering, Arusha P.O. Box 447, Tanzania
Email:
Jacob B. Lisuma,
Jacob B. Lisuma
Institution: Tobacco Research Institute of Tanzania (TORITA), Tabora P.O. Box 431, Tanzania
Email:
Nelson Mpumi,
Nelson Mpumi
Institution: Nelson Mandela African Institution of Science and Technology (NM-AIST), School for Materials, Energy, Water, Environmental Science and Engineering, Arusha P.O. Box 447, Tanzania
Email:
Aloyce I. Amasi,
Aloyce I. Amasi
Institution: Nelson Mandela African Institution of Science and Technology (NM-AIST), School for Materials, Energy, Water, Environmental Science and Engineering, Arusha P.O. Box 447, Tanzania
Email:
Jerome M. Mwimanzi,
Jerome M. Mwimanzi
Institution: Tanzania Atomic Energy Commission, Directorate of Nuclear Technology and Technical Services, Arusha P.O. Box 743, Tanzania
Email:
Furaha M. Chuma,
Furaha M. Chuma
Institution: Tanzania Atomic Energy Commission, Directorate of Nuclear Technology and Technical Services, Arusha P.O. Box 743, Tanzania
Email:
Thomas T. Kivevele,
Thomas T. Kivevele
Institution: Nelson Mandela African Institution of Science and Technology (NM-AIST), School for Materials, Energy, Water, Environmental Science and Engineering, Arusha P.O. Box 447, Tanzania
Email:
Kelvin M. Mtei
Kelvin M. Mtei
Institution: Nelson Mandela African Institution of Science and Technology (NM-AIST), School for Materials, Energy, Water, Environmental Science and Engineering, Arusha P.O. Box 447, Tanzania
Email:
Growing concern has been expressed about uranium (U) accumulation in agricultural soils caused by the long-term application of mineral fertilizers. More than 80% of naturally occurring U transfers from phosphate rock (PR), the raw material used in mineral fertilizer production, to phosphorus (P) fertilizers. These fertilizers are then distributed on agricultural soils, where the U could ac...
Posted 6 months ago
Paul Ikhurionan,
Paul Ikhurionan
Institution:
Email:
Imuwahen Mbarie
Imuwahen Mbarie
Institution:
Email:
IntroductionAdolescent headaches significantly impact their daily functioning, academic performance, and quality of life. The occurrence of headaches is influenced by genetics, psychological stressors, and environmental exposures. Understanding these influences is crucial for effective management strategies.AimTo determine the prevalence, characteristics, and associated factors of headache...
Posted 6 months ago
Zeynep Bal,
Zeynep Bal
Institution: Laboratory of Signal Transduction, WPI Immunology Frontier Research Center (WPI-IFReC), Osaka University, 3-1 Yamada-oka, Suita 565-0871, Osaka, Japan
Email:
Nobuyuki Takakura
Nobuyuki Takakura
Institution: Laboratory of Signal Transduction, WPI Immunology Frontier Research Center (WPI-IFReC), Osaka University, 3-1 Yamada-oka, Suita 565-0871, Osaka, Japan
Email:
Osteonecrosis of the femoral head (ONFH) is a vascular disease of unknown etiology and can be categorized mainly into two types: non-traumatic and traumatic ONFH. Thus, understanding osteogenic–angiogenic coupling is of prime importance in finding a solution for the treatment of ONFH. Hydrogels are biomaterials that are similar to the extracellular matrix (ECM). As they are able to mimic...
Posted 5 months ago
Elain Fu,
Elain Fu
Institution: School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA
Email:
Khadijeh Khederlou,
Khadijeh Khederlou
Institution: School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA
Email:
Noël Lefevre,
Noël Lefevre
Institution: School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA
Email:
Stephen A. Ramsey,
Stephen A. Ramsey
Institution: School of Electrical Engineering and Computer Science, Oregon State University, Corvallis, OR 97331, USA
Email:
Matthew L. Johnston,
Matthew L. Johnston
Institution: School of Electrical Engineering and Computer Science, Oregon State University, Corvallis, OR 97331, USA
Email:
Lael Wentland
Lael Wentland
Institution: School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, OR 97331, USA
Email:
Electrochemical detection, with its advantages of being rapid, multi-time point, compatible with cost-effective fabrication methods, and having the potential for miniaturization and portability, has great promise for point-of-care drug monitoring. However, a continuing challenge concerns the robust and sensitive electrochemical detection of pharmaceutical analytes from biological fluids. T...
Posted 5 months ago
Physics Maths Engineering
Fernando Viadero-Monasterio,
Fernando Viadero-Monasterio
Institution: Mechanical Engineering Department, Advanced Vehicle Dynamics and Mechatronic Systems (VEDYMEC), Universidad Carlos III de Madrid, Avda. de la Universidad 30, 28911 Leganés, Spain
Email:
Luciano Alonso-Rentería,
Luciano Alonso-Rentería
Institution: Control Engineering Group, Universidad de Cantabria, 39005 Santander, Spain
Email:
Juan Pérez-Oria,
Juan Pérez-Oria
Institution: Control Engineering Group, Universidad de Cantabria, 39005 Santander, Spain
Email:
Fernando Viadero-Rueda
Fernando Viadero-Rueda
Institution: Structural and Mechanical Engineering Department, Universidad de Cantabria, 39005 Santander, Spain
Email:
The introduction of advanced driver assistance systems has significantly reduced vehicle accidents by providing crucial support for high-speed driving and alerting drivers to imminent dangers. Despite these advancements, current systems still depend on the driver’s ability to respond to warnings effectively. To address this limitation, this research focused on developing a neural network...
Posted 5 months ago
Leena Shwashreh,
Leena Shwashreh
Institution: Leicester School of Architecture, De Montfort University, Leicester LE1 9BH, UK
Email:
Ahmad Taki,
Ahmad Taki
Institution: Leicester School of Architecture, De Montfort University, Leicester LE1 9BH, UK
Email:
Mike Kagioglou
Mike Kagioglou
Institution: Research and Business Innovation, De Montfort University, Leicester LE1 9BH, UK
Email:
This research delves into the intricate realm of social housing flat units within tower blocks in Leicester, as a microcosm that serves as a perfect reflection of the larger problem of fuel poverty among social housing systems within the UK. The multifaceted approach intertwines energy efficiency upgrades, indoor comfort, and resident satisfaction. Rooted in a comprehensive methodology, th...
Posted 5 months ago
Omar Ali Shaban Al-Awad,
Omar Ali Shaban Al-Awad
Institution: School of Agriculture and Environment, University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia
Email:
Kit Stasia Prendergast,
Kit Stasia Prendergast
Institution: School of Molecular and Life Sciences, Curtin University, Kent Street, Bentley, Perth, WA 6102, Australia
Email:
Alan Robson,
Alan Robson
Institution: School of Agriculture and Environment, University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia
Email:
Zed Rengel
Zed Rengel
Institution: School of Agriculture and Environment, University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia
Email:
Soil ammonium toxicity can decrease plant growth, and many crop species have low resistance to ammonium, including canola, an economically important crop. Different genotypes may differ in their resistance to ammonium toxicity, and therefore determining if there are genotypes that exhibit variation in their ability to tolerate soil ammonium is a research priority. Here, we evaluate how soi...
Posted 5 months ago
Physics Maths Engineering
Arash Mousaei,
Arash Mousaei
Institution: Department of Computer and Electrical Engineering, University of Tabriz, Tabriz 51666-16471, Iran
Email:
Yahya Naderi
Yahya Naderi
Institution: Department of Electronic and Electrical Engineering, University of Strathclyde, Glasgow G1 1XQ, UK
Email:
This article presents a novel approach to address the critical issues of stable rotation and energy efficiency in electric vehicles (EVs). To achieve these objectives, we propose a comprehensive control system that leverages the power of optimization through optimal predictive control methods. The central idea revolves around minimizing the predicted tracking error for future time steps by...
Posted 5 months ago
Rebecca Strawbridge,
Rebecca Strawbridge
Institution: Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AF, UK
Email:
Nefize Yalin,
Nefize Yalin
Institution: Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AF, UK
Email:
Stelios Orfanos,
Stelios Orfanos
Institution: South London & Maudsley NHS Foundation Trust, Maudsley Hospital, Denmark Hill, London SE5 8AZ, UK
Email:
Allan H. Young
Allan H. Young
Institution: Department of Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London SE5 8AF, UK
Email:
Acetazolamide, a carbonic anhydrase inhibitor, is used to treat a variety of ailments. It has been highlighted for its potential to benefit people with bipolar disorders, for whom there are clear current unmet treatment needs. This scoping review sought to synthesise all available evidence related to the potential effects of acetazolamide on symptoms related to bipolar disorder, acceptabil...
Posted 5 months ago
Christopher Ihinegbu,
Christopher Ihinegbu
Institution: Institute for Environment and Human Security, United Nations University, UN Campus, Platz der Vereinten Nationen 1, 53113 Bonn, Germany
Email:
Stefan Mönnich,
Stefan Mönnich
Institution: Institute for Environment and Human Security, United Nations University, UN Campus, Platz der Vereinten Nationen 1, 53113 Bonn, Germany
Email:
Thecla Akukwe
Thecla Akukwe
Institution: Department of Geography, University of Nigeria, Nsukka 410001, Nigeria
Email:
The evidence for the capacity of mangrove forests for coastal protection gained more importance within the recent decade because of important international agreements, such as the Sustainable Development Goals and Sendai Framework for Disaster Risk Reduction. However, the degree to which researchers agree on the capacity of mangroves to reduce coastal hazards is not fully established. This...
Posted 5 months ago
Nathan Shugg,
Nathan Shugg
Institution:
Email:
Michael E. O’Callaghan
Michael E. O’Callaghan
Institution:
Email:
AbstractIn this critical review, we explore the study design, strengths, and limitations of landmark trial “Anticholinergic therapy vs. onabotulinumtoxinA for urgency urinary incontinence”. This trial was the first to directly compare two key treatment options for urge urinary incontinence – anticholinergic medication and intravesical botox, and still influen...
Posted 5 months ago
Ivan Thia
Ivan Thia
Institution:
Email:
Abstract
Background
Increased usage of cross sectional imaging for a variety of indications, in particular CT imaging, has led to an increased detection of renal and ureteric masses. Benign ureteric masses are rare, with 95% of identified tumours consisting of transitional cell carcinoma (TCC). Ig...
Posted 5 months ago
Brent Cleveland,
Brent Cleveland
Institution:
Email:
Michael Borofsky
Michael Borofsky
Institution:
Email:
Abstract
Background
Nephrocalcinosis is often asymptomatic but can manifest with renal colic or hematuria. There is no reported association between nephrocalcinosis and renal vascular malformations, which may also be a source of hematuria. We herein present a case of a patient with hematuria relat...
Posted 5 months ago
Robert E Hurst
Robert E Hurst
Institution:
Email:
The article "Does the biomarker search paradigm need re-booting?" discusses the challenges in developing non-invasive biomarkers for bladder cancer recurrence and progression. Despite extensive research, no commercially available biomarkers match the sensitivity and specificity of cystoscopy, the current gold standard. The author suggests that conventional approaches to biomarker discovery are ...
Posted 5 months ago
Tanan Bejrananda,
Tanan Bejrananda
Institution:
Email:
Pitchaya Pliensiri
Pitchaya Pliensiri
Institution:
Email:
Abstract
Background
Radical prostatectomy (RP) has been considered primary treatment for localized prostate cancer. Biochemical recurrence (BCR) occur approximately 20–30% in five year after RP. We aim to develop a novel nomogram to predict BCR-free survival (BCRFS) and performed external valida...
Posted 5 months ago
Haidar Hadri bin Abd Wahab,
Haidar Hadri bin Abd Wahab
Institution:
Email:
Michael O’Callaghan
Michael O’Callaghan
Institution:
Email:
AbstractIn this critical review, we explore the study design, strengths and limitations of the paper: “Two-Year Outcomes of Sacral Neuromodulation Versus OnabotulinumtoxinA for Refractory Urgency Urinary Incontinence: A Randomized Trial.” The paper reports 24 month follow-up data of the landmark ROSETTA trial. This multi-centre, open-labelled parallel randomise...
Posted 5 months ago
Shelby Rauh,
Shelby Rauh
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Bradley S. Johnson,
Bradley S. Johnson
Institution:
Email:
Aaron Bowers,
Aaron Bowers
Institution:
Email:
Daniel Tritz,
Daniel Tritz
Institution:
Email:
Benjamin Matthew Vassar
Benjamin Matthew Vassar
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Abstract
Background
Reproducibility is essential for the integrity of scientific research. Reproducibility is measured by the ability of different investigators to replicate the outcomes of an original publication using the same materials and procedures. Unfortunately, reproducibility is not curre...
Posted 5 months ago
Tushar Patial,
Tushar Patial
Institution:
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Girish Sharma,
Girish Sharma
Institution:
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Pamposh Raina
Pamposh Raina
Institution:
Email:
The article "Traumatic penile amputation: a case report" presents the case of a 9-year-old boy who underwent replantation of his amputated penis, which ultimately failed. The replantation was performed using papaverine-aided microsurgical techniques. Despite initial success, the re-implanted penis experienced necrosis, leading to the loss of two-thirds of the tissue by day 12. The authors discu...
Posted 5 months ago
Wei Liu,
Wei Liu
Institution:
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Linxue Qian
Linxue Qian
Institution:
Email:
Purpose: Postpartum stress urinary incontinence (SUI) significantly impacts women's health and quality of life.
This study explores key risk factors, including clinical and ultrasound data, to improve early prevention strategies.
Method: Data were collected from pregnant women delivering at our hospital (March 2021 - January 2...
Posted 5 months ago
Shwan J Ahmed,
Shwan J Ahmed
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Ajay Mehta,
Ajay Mehta
Institution:
Email:
Peter Rimington
Peter Rimington
Institution:
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Background
Complications of suprapubic catheter insertion are rare but can be significant. We describe an unusual complication of a delayed bowel perforation following suprapubic catheter insertion.
Case Presentation
A gentleman presented with features of peritonitis and feculen...
Posted 5 months ago
Gaurav Aggarwal,
Gaurav Aggarwal
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Samiran Das Adhikary
Samiran Das Adhikary
Institution:
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Background
Rupture of the urinary collecting system with or without any perinephric extravasation is an extremely rare occurrence and usually known to occur following an obstructive pathology. Spontaneous or non-traumatic rupture, in the absence of any distal obstruction, though reported in literature, is not yet a proven entity and need...
Posted 5 months ago
William A Banks
William A Banks
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The article "Characteristics of compounds that cross the blood-brain barrier" discusses the mechanisms by which substances traverse the blood-brain barrier (BBB), focusing on transmembrane diffusion and transporters. It highlights that transmembrane diffusion is non-saturable and depends on the physicochemical properties of the substance. Additionally, the article notes that brain-to-blood effl...
Posted 5 months ago
Karen L Steinmetz,
Karen L Steinmetz
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Edward G Spack
Edward G Spack
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The article "The basics of preclinical drug development for neurodegenerative disease indications" provides an overview of the essential steps involved in transitioning a drug candidate from laboratory discovery to human clinical trials. It emphasizes the importance of preclinical studies in identifying lead candidates, developing scalable production methods, selecting optimal formulations, and...
Posted 5 months ago
Diana W Shineman,
Diana W Shineman
Institution:
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Howard M Fillit
Howard M Fillit
Institution:
Email:
The article "Meeting the unique challenges of drug discovery for neurodegenerative diseases" discusses the complexities and opportunities in developing therapeutics for conditions such as Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and multiple sclerosis. The authors emphasize the need for a multidisciplinary approach, integrating academic rese...
Posted 5 months ago
Priscilla Namaganda,
Priscilla Namaganda
Institution:
Email:
Jane Nakibuuka,
Jane Nakibuuka
Institution:
Email:
Mark Kaddumukasa,
Mark Kaddumukasa
Institution:
Email:
Elly Katabira
Elly Katabira
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Abstract
Background
Stroke is the second leading cause of death above the age of 60 years, and the fifth leading cause in people aged 15 to 59 years old as reported by the World Health Organization global burden of diseases. Stroke in the young is particularly tragic because of the potential to ...
Posted 5 months ago
A. Bersano,
A. Bersano
Institution:
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J. Engele,
J. Engele
Institution:
Email:
M.K.E. Schäfer
M.K.E. Schäfer
Institution:
Email:
Abstract
Starting from the perspective of an immune-privileged site, our knowledge of the inflammatory processes within the central nervous system has increased rapidly over the last 30 years, leading to a rather puzzling picture today. Of particular interest is the emergence of disease- and injury-specific inflammatory responses within t...
Posted 5 months ago
Raed Alroughani,
Raed Alroughani
Institution:
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Alexey Boyko
Alexey Boyko
Institution:
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Background
Pediatric-onset multiple sclerosis (POMS) prevalence and incidence rates are increasing globally. No disease-modifying therapy are approved for MS pediatric population. Hence, we aim to review the literature on POMS to guide treating physicians on the current understanding of diagnosis and management of pediatric MS.
Methods
The authors performed a literature search and reviewed th...
Posted 5 months ago
R. Dersch,
R. Dersch
Institution:
Email:
I. Toews,
I. Toews
Institution:
Email:
H. Sommer,
H. Sommer
Institution:
Email:
S. Rauer,
S. Rauer
Institution:
Email:
J. J. Meerpohl
J. J. Meerpohl
Institution:
Email:
Background;
Many aspects of clinical management of Lyme neuroborreliosis are subject to intense debates. Guidelines show considerable variability in their recommendations, leading to divergent treatment regimes. The most pronounced differences in recommendations exist between guidelines from scientific societies and from patient advocacy groups. Assessment of the methodological quality of these c...
Posted 5 months ago
Karl B Alstadhaug,
Karl B Alstadhaug
Institution:
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Espen Benjaminsen
Espen Benjaminsen
Institution:
Email:
The article "Synesthesia and Migraine: Case Report" presents a unique case of a 40-year-old woman with a cyclic mood disorder who experienced synesthetic sensations exclusively during visual migraine auras. Specifically, she reported an intense taste of lemon accompanied by salivation when staring at bright light during the aura phase. This case supports the hypothesis of anomalous cortical pro...
Posted 5 months ago
Dereje Melka,
Dereje Melka
Institution:
Email:
Abenet Tafesse,
Abenet Tafesse
Institution:
Email:
James H. Bower,
James H. Bower
Institution:
Email:
Demeke Assefa
Demeke Assefa
Institution:
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The article "Prevalence of sleep disorders in Parkinson’s disease patients in two neurology referral hospitals in Ethiopia" investigates the prevalence of sleep disorders among Parkinson's disease (PD) patients in Ethiopia. The study found that all 155 surveyed patients reported some form of sleep problem, with over 43.9% scoring above 18 on the Parkinson's Disease Sleep Scale (PDSS-2), indic...
Posted 5 months ago
Matthias Löhle,
Matthias Löhle
Institution:
Email:
Heinz Reichmann
Heinz Reichmann
Institution:
Email:
The article "Controversies in Neurology: why monoamine oxidase B inhibitors could be a good choice for the initial treatment of Parkinson's disease" examines the potential benefits of initiating treatment with monoamine oxidase B (MAO-B) inhibitors in early-stage Parkinson's disease (PD). The authors discuss the favorable safety profile and possible neuroprotective effects of MAO-B inhibitors, ...
Posted 5 months ago
Rohit Gummi,
Rohit Gummi
Institution:
Email:
Ross Smith,
Ross Smith
Institution:
Email:
Raghav Govindarajan
Raghav Govindarajan
Institution:
Email:
Abstract
Background
Student Interest Group in Neurology (SIGN) chapters across the medical schools in the United States provide opportunities for medical students to participate in clinical, research, and service activities in neurology. Despite these, applicants for the field of neurology have tr...
Posted 5 months ago
