All Articles

Reduced immune system responsiveness in fibromyalgia - a pilot study

author list,

author list

Institution: rnfinity

Email: info@rnfinity.com

Sophia Bjorkander,

Sophia Bjorkander

Institution: Department of Clinical Science and Education, Södersjukhuset,

Email: indre.ljungar@ki.se

Ernberg Malin,

Ernberg Malin

Institution: Department of Dental Medicine, Karolinska Institutet, and the Scandinavian Centre for Orofacial Neurosciences (SCON),

Email: indre.ljungar@ki.se

Inders Bileviciute-Ljungar

Institution: Department of Rehabilitation Medicine, Danderyds University Hospital and Dept. of Clinical Sciences, Karolinska Institutet (KIDS),

Email: indre.ljungar@ki.se

Fibromyalgia is characterized by widespread musculoskeletal and joint pain, stiffness, fatigue, and sleep and mood disorders. However, the involvement of the immune system in the pathways of fibromyalgia is unclear. The aim of this study was to explore the role of the immune system in comparison with healthy controls and in association with clinical symptoms. Thirteen women with fibromyalgia and 14 controls were included. Peripheral blood mononuclear cells were stimulated and analysed by flow cytometry, and interferon gamma (IFN-γ) and interleukins were measured. Among clinical symptoms, the fibromyalgia group showed decreased cold pain threshold. Immunologically, they had a higher percentage of monocytes, a lower percentage of CD19+ B-cells, and lower secretion of IFN-γ after stimulation. Decreased capacity to secrete IFN-γ was significantly correlated with decreased cold pain threshold in the fibromyalgia group. These results confirm the presence of immune aberrations in fibromyalgia, at least partially responsible for the associated pain.
Less

Posted 1 year ago

Profile of ectoparasites and biometric condition of snakehead (Channa striata Bloch 1793) collected from different habitats

author list

Institution: rnfinity

Email: info@rnfinity.com

Ilfam Zulfahmi,

Ilfam Zulfahmi

Institution: Department of Fisheries Resources Utilization, Faculty of Marine and Fisheries, Universitas Syiah Kuala

Email: Ilham.Zulfahmi@unsyiah.ac.id

Feizia Huslina,

Feizia Huslina

Institution: Ar-Raniry Banda Aceh 23111, Indonesia.

Email: Ilham.Zulfahmi@unsyiah.ac.id

Rizki Nanda,

Rizki Nanda

Institution: Department of Fisheries Resources Utilization, Faculty of Marine and Fisheries, Universitas Syiah Kuala

Email: Ilham.Zulfahmi@unsyiah.ac.id

Firman Nur,

Firman Nur

Institution: Graduate School of Mathematics and Applied Science, Universitas Syiah Kuala,

Email: Ilham.Zulfahmi@unsyiah.ac.id

Rian Djuanda,

Rian Djuanda

Institution: Ar-Raniry Banda Aceh 23111, Indonesia.

Email: Ilham.Zulfahmi@unsyiah.ac.id

Aldi Waliol Perdana

Institution: Department of Aquaculture, Faculty of Marine and Fisheries, Universitas Syiah Kuala,

Email: Ilham.Zulfahmi@unsyiah.ac.id

Studies related to the comparison of ectoparasites that infect snakehead from different habitats and their relationship to biometric conditions have not been widely studied. Thus, present study aimed to investigate the prevalence, intensity, dominance, and predilection of ectoparasites on snakehead collected from ditches, paddy fields, and swamps and correlate them with biometric conditions. In total of 90 snakehead fish were collected from ditches, paddy fields, and swamps. The observation of ectoparasites was performed on the gills, fins, and skin. The parameters measured in this study were ectoparasite profiles and biometric condition of fish. Specifically, the parameters of the ectoparasite profile included prevalence, intensity, dominance, and predilection. Meanwhile, the parameters of the biometric conditions were the length-weight relationship, the distribution of length and weight classes, and condition factors. Five species of ectoparasites that have been identified as Tetrahymena sp., Epistylis sp., Trichodina sp., Dactylogyrus sp., and Gyrodactylus sp. Tetrahymena sp. infection in snakehead was reported for the first time. The ditch habitat had the highest prevalence and intensity, which were 76.7% and 15.4 ectoparasites/fish, respectively. Tetrahymena sp. and Epistylis sp. were detected in sneakhead from all habitats, Trichodina sp. was detected at ditch and paddy field habitats, whereas, Gyrodactylus sp. and Dactylogyrus sp. were only found in swamp habitats. The gill was the predilection organ that most vulnerable to ectoparasite infection. Infected Snakehead tend to have lower average weight and length than healthy snakehead. Snakehead with a weight range of 115.2-145.2 g and a length range of 258.5-268.5 mm tend to be more vulnerable to ectoparasite infection compared to other sizes.Keywords:Tetrahymena sp.PrevalenceIntensityPredilectionLength-weight relationship
Less

Posted 1 year ago

Showing Page 14 to 14