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Biomedical

Growth and Progression of TRAMP Prostate Tumors in Relationship to Diet and Obesity

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Institution: rnfinity

Email: info@rnfinity.com

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Melissa J. L. Bonorden,

Melissa J. L. Bonorden

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Michael E. Grossmann,

Michael E. Grossmann

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Sarah A. Ewing,

Sarah A. Ewing

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Olga P. Rogozina,

Olga P. Rogozina

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Amitabha Ray,

Amitabha Ray

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Katai J. Nkhata,

Katai J. Nkhata

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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D. Joshua Liao,

D. Joshua Liao

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

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Joseph P. Grande,

Joseph P. Grande

Institution: Department of Pathology and Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA

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Margot P. Cleary

Margot P. Cleary

Institution: The Hormel Institute, University of Minnesota, Austin, MN 55912, USA

Email:

To clarify effects of diet and body weight on prostate cancer development, three studies were undertaken using the TRAMP mouse model of this disease. In the first experiment, obesity was induced by injection of gold thioglucose (GTG). Age of prostate tumor detection (~33 wk) and death (~43 wk) was not significantly different among the groups. In the second study, TRAMP-C2 cells were injected i...
Posted 6 months ago

Physics Maths Engineering

Climate Change and Livestock Production in Nigeria: Issues and Concerns

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Institution: rnfinity

Email: info@rnfinity.com

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CC Nwosu,

CC Nwosu

Institution:

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CC Ogbu

CC Ogbu

Institution:

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Nwosu and Ogbu (2011) provide a comprehensive overview of the challenges posed by climate change to livestock production in Nigeria. They emphasize the need for adaptive measures to address the adverse effects of climate variability on livestock health and productivity. The review underscores the importance of integrating environmental modifications, selective breeding, and nutritional adjustme...
Posted 6 months ago

Biomedical

Antiphospholipid antibodies in patients with antiphospholipid syndrome

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Institution: rnfinity

Email: info@rnfinity.com

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Slavica Dodig,

Slavica Dodig

Institution:

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Ivana Čepelak

Ivana Čepelak

Institution:

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Highlights • Antiphospholipid syndrome is a rare systemic autoimmune disease characterized by recurrent pregnancy morbidity or thrombosis in combination with the persistent presence of antiphospholipid antibodies in plasma/serum • Specialists in laboratory medicine should take responsibility for the entire analytical process, so that possible interferences are minimized, and physicians obtai...
Posted 6 months ago

Biomedical

Preanalytical, analytical and postanalytical considerations in circulating microRNAs measurement

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Institution: rnfinity

Email: info@rnfinity.com

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Mustapha Zendjabil

Mustapha Zendjabil

Institution: Faculty of Medicine, University of Oran 1 - Ahmed Ben Bella, Oran, Algeria

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Highlights • Methods used for miRNAs expression profiling are quantitative reverse transcription polymerase chain reaction, microarrays, next generation sequencing and droplet digital PCR • To obtain reproducible and accurate miRNAs expression profiling detection, it is crucial to strictly standardize the entire process, starting from choosing the specimen type until the normalization strate...
Posted 6 months ago

Biomedical

What did CRISPR-Cas9 accomplish in its first 10 years?

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Institution: rnfinity

Email: info@rnfinity.com

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Yehya Khlidj

Yehya Khlidj

Institution:

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It’s been 10 years now from the debut of clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) era in which gene engineering has never been so accessible, precise and efficient. This technology, like a refined surgical procedure, has offered the ability of removing different types of disease causing mutations and restoring key proteins activity with ease of...
Posted 6 months ago

Biomedical

Glucose inhibitor tubes in Croatian laboratories: are we doing well?

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Institution: rnfinity

Email: info@rnfinity.com

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Alen Vrtarić,

Alen Vrtarić

Institution:

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Nora Nikolac Gabaj,

Nora Nikolac Gabaj

Institution:

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Ivana Ćelap

Ivana Ćelap

Institution:

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Introduction Reliable and accurate measurement of blood glucose concentration is of crucial importance for making clinical decisions in diagnosis diabetes, gestational diabetes and impaired fasting glucose tolerance. Materials and methods Survey was performed in form of questionnaire. Questionnaire was sent to all Croatian laboratories (N = 204) in electronic form using SurveyMonkey cloud-bas...
Posted 6 months ago

Biomedical

Extracellular vesicles and glycans

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Institution: rnfinity

Email: info@rnfinity.com

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Tamara Janković,

Tamara Janković

Institution:

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Miroslava Janković

Miroslava Janković

Institution:

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Highlights • Biological fluids contain nano-sized particles called extracellular vesicles • Extracellular vesicles properties reflect the physiological and pathological state of the parent cells • Extracellular vesicles as analytes are suitable for use in liquid biopsy-based real-time diagnostics • Glycans, complex oligosaccharides, are distinct components of extracellular vesicles mem...
Posted 6 months ago

Physics Maths Engineering

Introducing prediction intervals for sample means

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Institution: rnfinity

Email: info@rnfinity.com

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Molly E. Contini,

Molly E. Contini

Institution:

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Jeffrey R. Spence,

Jeffrey R. Spence

Institution:

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David J. Stanley

David J. Stanley

Institution:

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Researchers and practitioners are typically familiar with descriptive statistics and statistical inference. However, outside of regression techniques, little attention may be given to questions around prediction. In the current paper, we introduce prediction intervals using fundamental concepts that are learned in descriptive and inferential statistical training (i.e., sampling error, standard dev...
Posted 6 months ago

Physics Maths Engineering

Prediction interval

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Institution: rnfinity

Email: info@rnfinity.com

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Abdurrahman Coskun

Abdurrahman Coskun

Institution:

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Highlights • Prediction interval has a great potential to be used in laboratory medicine • It is a powerful tool for computing personalized reference interval and reference change value • It can be used to assess the stability of analytical systems • It can be used in monitoring the accuracy and reproducibility of analytical systems Monitoring is indispensable for assessing disease pr...
Posted 6 months ago

Biomedical

Machine learning-mediated Passiflora caerulea callogenesis optimization

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Institution: rnfinity

Email: info@rnfinity.com

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Marziyeh Jafari,

Marziyeh Jafari

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Mohammad Hosein Daneshvar

Mohammad Hosein Daneshvar

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Callogenesis is one of the most powerful biotechnological approaches for in vitro secondary metabolite production and indirect organogenesis in Passiflora caerulea. Comprehensive knowledge of callogenesis and optimized protocol can be obtained by the application of a combination of machine learning (ML) and optimization algorithms. In the present investigation, the callogenesis responses (i.e., ca...
Posted 6 months ago

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