Wenjie Liu,
Wenjie Liu
Institution: NULL
Email:
Bin Yu,
Bin Yu
Institution: NULL
Email:
Furong Lv,
Furong Lv
Institution: NULL
Email:
Kaiwen Liang,
Kaiwen Liang
Institution: NULL
Email:
Zhibo Xiao
Zhibo Xiao
Institution: NULL
Email:
Background and Objectives: The existing recommendations for female pelvic magnetic susceptibility weighted imaging MRI (FP-SWI) have not been optimized to capture the disease characteristics of the female pelvis. Therefore, it is imperative to explore acquisition parameters before conducting larger-scale studies. To establish optimized flip angle (FA) for acquiring FP-SWI to improve the image qual...
Posted 7 months ago
Vaishali Kapila,
Vaishali Kapila
Institution: NULL
Email:
Arjun G Kalra,
Arjun G Kalra
Institution: NULL
Email:
David L Stockman
David L Stockman
Institution: NULL
Email:
Hereditary leiomyomatosis and renal cell carcinoma (HLRCC) syndrome is believed to result from an autosomal dominant mutation in the fumarate hydratase (FH) gene on chromosome 1. It is characterized by leiomyomas, mainly uterine or cutaneous, and renal cell carcinoma (RCC). The most common type of RCC associated with HLRCC is type II papillary RCC although other types are seen. Of note, chromophob...
Posted 7 months ago
Karel Mercken,
Karel Mercken
Institution: NULL
Email:
Brecht Van Berkel,
Brecht Van Berkel
Institution: NULL
Email:
Liesbeth De Wever
Liesbeth De Wever
Institution: NULL
Email:
In hereditary leiomyomatosis and renal cell carcinoma syndrome, fumarate hydratase–deficient renal cell carcinomas typically present as aggressive, unilateral, often cystic masses with heterogeneous enhancement. These tumors can metastasize early, making appropriate imaging and staging critical for diagnosis and management.
Teaching point: When a renal lesion suspected of RCC is identified in...
Posted 7 months ago
Sophie Ferlicot,
Sophie Ferlicot
Institution: NULL
Email:
Pierre-Alexandre Just,
Pierre-Alexandre Just
Institution: NULL
Email:
Eva Compérat,
Eva Compérat
Institution: NULL
Email:
Etienne Rouleau,
Etienne Rouleau
Institution: NULL
Email:
Frédérique Tissier,
Frédérique Tissier
Institution: NULL
Email:
Christophe Vaessen,
Christophe Vaessen
Institution: NULL
Email:
Stéphane Richard
Stéphane Richard
Institution: NULL
Email:
Background
Hereditary papillary renal cell carcinoma (HPRCC) is a rare autosomal dominant disease characterized by the development of multiple and bilateral papillary type I renal cell carcinomas (RCC) and papillary adenomas caused by activating mutations in the MET proto-oncogene. Classically, distinctive histological features of RCC are described according to the familial renal cell carcinoma s...
Posted 7 months ago
Tina Kamani,
Tina Kamani
Institution: NULL
Email:
Parsa Charkhchi,
Parsa Charkhchi
Institution: NULL
Email:
Afshan Zahedi,
Afshan Zahedi
Institution: NULL
Email:
Mohammad R. Akbari
Mohammad R. Akbari
Institution: NULL
Email:
Non-medullary thyroid cancer (NMTC) is the most common type of thyroid cancer. With the increasing incidence of NMTC in recent years, the familial form of the disease has also become more common than previously reported, accounting for 5–15% of NMTC cases. Familial NMTC is further classified as non-syndromic and the less common syndromic FNMTC. Although syndromic NMTC has well-known genetic risk...
Posted 7 months ago
Yue Yin Xia,
Yue Yin Xia
Institution: NULL
Email:
Joanne Kotsopoulos
Joanne Kotsopoulos
Institution: NULL
Email:
BRCA1 and BRCA2 mutation carriers face an elevated lifetime risk of developing ovarian cancer. Oral contraceptives have been shown to significantly decrease the risk of ovarian cancer by approximately 50% in this high-risk population. Changes in contraceptive formulations and patterns of use over time have introduced lower hormonal dosages, different steroid types and non-oral routes of administra...
Posted 7 months ago
Fangfang Gao,
Fangfang Gao
Institution: NULL
Email:
Dejian Gu,
Dejian Gu
Institution: NULL
Email:
He Zhang,
He Zhang
Institution: NULL
Email:
Chao Shi,
Chao Shi
Institution: NULL
Email:
Feng Du,
Feng Du
Institution: NULL
Email:
Bo Zheng,
Bo Zheng
Institution: NULL
Email:
Huijuan Wu,
Huijuan Wu
Institution: NULL
Email:
Yanqiu Zhao
Yanqiu Zhao
Institution: NULL
Email:
Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare autosomal dominant syndrome caused by a germline mutation in the fumarate hydratase (FH) gene that manifests with cutaneous leiomyomas, uterine fibroids, and renal cell cancer (RCC). Patients with HLRCC-associated RCC (HLRCC-RCC) have aggressive clinical courses, but there is no standardized therapy for advanced HLRCC-RCC. In this s...
Posted 7 months ago
Annmarie Taheny,
Annmarie Taheny
Institution: NULL
Email:
Haylie McSwaney,
Haylie McSwaney
Institution: NULL
Email:
Julia Meade
Julia Meade
Institution: NULL
Email:
Current National Comprehensive Cancer Network ® (NCCN ®) guidelines for Colorectal Genetic/Familial High-Risk Assessment provide limited guidance for genetic testing for individuals with already diagnosed hereditary cancer conditions. We are presenting the case of a 36-year-old woman who was diagnosed with Lynch Syndrome at age 23 after genetic testing for a familial variant (c.283del) in the ML...
Posted 7 months ago
Maneesh Singh
Maneesh Singh
Institution: Kansas City university
Email:
Introduction.
Hereditary non-polyposis colorectal cancer is also known as Lynch syndrome. It is autosomal dominant and
is one of the most common causes of inherited colon cancer. A family history of colorectal cancer in
first-degree relatives in two generations, and one case before the age of 50 is seen with Lynch syndrome
The purpose of this paper is to provide a review of hereditary non-p...
Posted 7 months ago
Akihiro Ohmoto,
Akihiro Ohmoto
Institution: NULL
Email:
Naomi Hayashi,
Naomi Hayashi
Institution: NULL
Email:
Shunji Takahashi,
Shunji Takahashi
Institution: NULL
Email:
Arisa Ueki
Arisa Ueki
Institution: NULL
Email:
Adrenocortical carcinoma (ACC) and pheochromocytoma/paraganglioma (PPGL) are two rare types of adrenal gland malignancies. Regarding hereditary tumors, some patients with ACC are associated with with Li-Fraumeni syndrome (LFS), and those with PPGL with multiple endocrine neoplasia type 2. Recent studies have expanded this spectrum to include other types of hereditary tumors, such as Lynch syndrome...
Posted 7 months ago
