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Biomedical

An Overview of the Epigenetic Modifications in the Brain under Normal and Pathological Conditions

Epigenetic changes are changes in gene expression that do not involve alterations to the DNA sequence. These changes lead to establishing a so-called epigenetic code that dictates which and when genes are activated, thus orchestrating gene regulation and playing a central role in development, health, and disease. The brain, being mostly formed by cells that do not undergo a renewal process...
Posted 4 months ago

Biomedical

The Roles of Various Immune Cell Populations in Immune Response against Helminths

Helminths are multicellular parasites that are a substantial problem for both human and veterinary medicine. According to estimates, 1.5 billion people suffer from their infection, resulting in decreased life quality and burdens for healthcare systems. On the other hand, these infections may alleviate autoimmune diseases and allergy symptoms. The immune system is programmed to combat infec...
Posted 4 months ago

Physics Maths Engineering

Distribution and Metabolic Activities of Marine Microbes in Response to Natural and Anthropogenic Stressors

As a consequence of climate change and increased human pressure, aquatic ecosystems are experiencing natural and anthropogenic stressors and events such as temperature warming, acidification, biodiversity loss, and degraded water quality. To understand the response of marine ecosystems to environmental and anthropogenic pressures, integration of long-term and large-scale monitoring of marine commu...
Posted 4 months ago

Biomedical

Synthesis of Bisoxazole and Bromo-substituted Aryloxazoles

Herein, we report a bisoxazole derivative as well as a bromo-substituted oxazole derivatives via a simple approach. The synthesis begins with an inexpensive and readily available starting material, such as 2,5-dimethoxybenzaldehyde, hydroquinone, and p-toluenesulfonylmethyl isocyanide (TosMIC). This approach relies on the Van Leusen oxazole method and electrophilic aromatic bromination. Th...
Posted 4 months ago

Physics Maths Engineering

Nitrogen-vacancy centers in diamond: discovery of additional electronic states

Abstract Nitrogen-vacancy (NV) defect centers in diamond are key to applications in quantum sensing and quantum computing. They create localized electronic states in the diamond lattice with distinct population relaxation pathways following photoexcitation that ultimately enable its unique properties. The defect is known to exist in two charge state...
Posted 4 months ago

Physics Maths Engineering

Recent progress in undoped group-IV heterostructures for quantum technologies

Abstract Silicon has been a core material for digital computing owing to its high mobility, stability oxide interface, mature manufacturing technologies for more than half a century. While Moore’s law seems to further advance via various technologies to extend its expiration date, some intractable problems that requires processing times growing ex...
Posted 4 months ago

Physics Maths Engineering

Efficient characterization of blinking quantum emitters from scarce data sets via machine learning

Abstract Single photon emitters are core building blocks of quantum technologies, with established and emerging applications ranging from quantum computing and communication to metrology and sensing. Regardless of their nature, quantum emitters universally display fluorescence intermittency or photoblinking: interaction with the environment can caus...
Posted 4 months ago

Humanities and Arts

Task-Based Language Teaching

Task-Based Language Teaching by Daniel O. Jackson is part of the Cambridge Elements series published by Cambridge University Press in 2022. This book adopts a cognitive-interactionist stance on language learning, and serves as a guide to task-based language teaching (TBLT) for language instructors, teacher educators, and other interested parties. In response to a lack of practical guidance...
Posted 4 months ago

Humanities and Arts

Investigating Mixed Methods Research in Applied Linguistics: Methodological Avoidance and Possible Barriers in the Field

The field of applied linguistics is becoming increasingly transdisciplinary as recognition for the need to approach empirical questions from a variety of epistemological and theoretical perspectives grows (Douglas Fir Group, 2016). One methodological approach that holds promise for advancing sophisticated inquiry into complex issues of applied linguistics is mixed methods research (MMR); h...
Posted 4 months ago

Humanities and Arts

Usability of ChatGPT in Second Language Acquisition: Capabilities, Effectiveness, Applications, Challenges, and Solutions

In the realm of language acquisition, the integration of Artificial Intelligence (AI) presents a promising frontier. However, gaps exist in understanding the practical application of AI-driven tools, particularly in second language learning contexts. This study delves into the usability of ChatGPT, an advanced AI language model, within the domain of second language acquisition. This paper ...
Posted 4 months ago

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